10 Best Calming Products For Cats 2025 in the United States

The FELIWAY Optimum Enhanced Calming Pheromone is a 30-day refill designed to reduce stress-related behaviors in cats, such as scratching, urine spraying, and excessive hiding. As a non-sedating and drug-free solution, it releases pheromone analogs to provide a natural, reassuring message to cats, helping them feel more at ease. This product is easy to use—simply plug the diffuser into an open outlet with good air circulation, and it will work continuously for up to 30 days.

It’s important to use the FELIWAY diffuser with its specific refills for optimal results. One diffuser covers up to 700 square feet, and it should be replaced every six months, with refills changed monthly. Backed by over 25 years of research and recommended by vets, it’s a reliable choice for many cat owners.

However, it may not be universally effective for all cats, and the need to replace refills and diffusers regularly could be a recurring cost. Additionally, while it is safe for cats, humans, and other pets, it carries a specific scent (Mimosa) that may not appeal to everyone. This product is most beneficial for cat owners dealing with noticeable signs of feline stress in their homes.

The FELIWAY MultiCat Calming Pheromone, 30 Day Refill, is a pheromone product designed to reduce tension and conflict between cats. It mimics a mother cat’s natural pheromones, which can help to soothe and comfort multiple cats living in the same household. This product is drug-free and non-sedating, making it a safe choice for both cats and humans. Safety is further assured as it does not affect other pets in the home.

The product is easy to use; simply plug the diffuser into an open outlet, and it will continuously release the calming pheromone for up to 30 days. However, to maintain effectiveness, the vial needs to be replaced monthly, and the diffuser every six months. This could be seen as a recurring cost and minor inconvenience for some users. The product is backed by scientific research and 25 years of expertise, with 84% of cat owners reporting a significant improvement in cat conflicts.

The compact dimensions (1.75 x 1.75 x 3.25 inches) make it a discreet addition to the home. One limitation is that it requires a specific FELIWAY diffuser, so compatibility with other brands is not an option. It is an excellent product for cat owners seeking a non-invasive and scientifically supported method to reduce tensions between their pets.

The Comfort Zone Multi Cat Calming Diffuser Refills are a drug-free, fragrance-free solution designed to reduce tension and aggressive behaviors in multi-cat households. This product uses calming pheromones to help manage issues like swatting, scratching, and fighting. The refills are compatible only with Comfort Zone diffusers, which are reusable for up to 12 months. Each refill lasts about 30 days, providing up to six months of continuous calming support with the included six-pack value set.

The diffusers effectively cover up to 400 square feet, making them suitable for larger rooms where your cats spend most of their time. Safety is a key aspect, with the product meeting Intertek electrical safety and certified to UL standards, and an automatic shut-off feature to prevent overheating. While the diffuser is easy to use, it requires proper placement—upright and not obstructed by furniture for optimal performance.

Users should note that the product might not work with other brands’ diffusers and must be replaced monthly for consistent effectiveness. Additionally, the lack of fragrance might be a plus for some, but it could also mean it's less noticeable when it's working. This calming solution may be particularly beneficial for households with more than one cat experiencing behavioral issues.